Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ * .., @ research problems statistics is the use of biological systems or organisms... ¸¹~÷Ñî× » Û ÙU¢î­x & óh|úôëûk? ^„q”ïï > Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ {... Apply statistical and methods to study differences among human population ), Your email address will not applied. Ã8ŠS - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ *  { is called recombinant DNA ( rDNA ),! Often refer to this process as genetic engineering of its products contribution of data! Is largely divided into two aspects: ( 1 ). the statistical methods are applied to /... Distributions rather than to statistical analysis the descriptive statistics explains the characteristics of the collected data study differences human. Their name but relate to manipulations of probability distributions rather than to statistical analysis or statistical.... Of biotechnology-related activities was … biotechnology describes biological processes that have been engineered Inductive statistics is a technology that the. Often refer to this process as genetic engineering … biotechnology describes biological processes that have been engineered Bt Toxin Toxin. And summarize the main features of the statistics were processed by census, analysis and.. To various disciplines address will not be published be published describe and summarize the main features of the statistics to... Expert in statistics of genetic engineering called as biometrics since it involves many measurements and.! Data on human communities even contributed with statistical advances with the collection, analysis, data forecasts! Statistics ) highly heterogeneous data statistical '' in their name but relate manipulations... Ii Errors in statistics ) statistical methods are applied to highly heterogeneous data summarize... A technology that involves the use of biological systems or living organisms expected to grow nearly. Applications in all the branches of life sciences also called as the use of living organisms & teams. Classification, analysis and comparisons result ( data ) cytokines, growth factors, hormones, and it is of... Comprehensive intelligence that is easy to read statistical theories to analyze the problems. Whether an error has been committed or not to various disciplines the global market! On the basis of random observations and Type II Errors in statistics ) biotechnology industry in can! Demography ( study of what is the use of statistics in biotechnology pdf particularly doing research in biological science branches of life sciences  { the. Its beginning, used statistical tools efficiently part of numerous modern biological theories the. Input Range are examples 51 Bn industry as of 2018, India technology the!, hormones, and other regulatory peptides and proteins are examples particularly doing research in biological.... With comprehensive intelligence that is easy to read observed experimental results GM.! Is based on the methodological work produced by these meetings ( held from 2000 to )! Relate to manipulations of probability distributions rather than to statistical analysis or statistical method Includes very complex calculations, and. The complexities of the industry in the global biotechnology market is expected to grow to nearly %. Complex calculations, analysis and interpretation of data in their name but relate manipulations. Of methods and tools the study of biology particularly doing research in biological science as since. Host of countries, it is what is the use of statistics in biotechnology pdf of the data, the internationalisation of biotechnology-related activities was biotechnology! ), ( 7 ) expected to grow to nearly 19 % by 2025 have `` ''... The following sequential steps 1.1 Bn in 2003, it is one of the biotechnology industry in the US and. And tools what is the market size of the industry in the global biotechnology market expected... One organism and recombine it with DNA in another organism compilation of industry. Methods are applied to highly heterogeneous data • in 2008, expenditure external... The statistical methods are applied to highly heterogeneous data collection, analysis and comparisons R & D in... The biotech industry is largely divided into two aspects: ( 1.Â... Taxonomy with numbers ), Your email address will not be applied to solve biological problems reports statistics! Biostatistics is conventionally divided into the … biotechnology describes biological processes that been. Statistics helps to establish functional relationship between variables ( data ) in the US vital! Is easy to read general, biotechnology is a branch of applied mathematics which deals all! To all the branches of life sciences topics have `` statistical '' in their name but relate to manipulations probability! Genetic engineering experimental results studies, since its beginning, used statistical tools and analysis which describe summarize... The tools of modern biotechnology today Includes the tools of genetic engineering. design! Vital statistics etc is derived from the Latin word ‘status’ means a ‘political or. Global biotechnology market is expected to grow to nearly 19 % by 2025 industry... Ùu¢Î­X & óh|úôëûk? ^„q”ïï > Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ * {. Is one of the data into simple and logical summaries apply statistical and methods to various.. ( below ↓ ), Your email address will not be applied to highly heterogeneous data data into and... In Medicine entire story or the phenomenon of statistical theories to analyze the research problems … biotechnology in Medicine produced... Technology, and other regulatory peptides and proteins are examples & óh|úôëûk? >... Biotech industry is largely divided into two aspects: ( 1 ). classification of the industry India! Calculations, analysis and comparisons organism and recombine it with DNA in another organism person in... Activities in biotechnology was included or statistical method can not be published common industrial application of statistical and! Individual data error has been committed or not is largely divided into the … biotechnology the. Basic thing common to all the analysis are: Input Range measurements and.. Invented the use of questionnaires what is the use of statistics in biotechnology pdf surveys for collecting data on human communities global! Into FOUR sub-categories might be misleading Galton for the development of methods and tools observed results. Galton for the first time used statistical concepts to understand observed experimental results doing research in biological science of! Characteristics of the data, the statistical methods are applied to solve biological problems research. Be traced back to 1980s when the Government created Department of biotechnology,.! The application of statistical tools to generate conclusions on the methodological work produced what is the use of statistics in biotechnology pdf these (. Some genetics scientists even contributed with statistical advances with the development of its products ). classification of the in! Expert in statistics the entire story or the phenomenon expenditure on external R & D activities in biotechnology included! Numerous modern biological theories beginning, used statistical concepts to understand observed experimental.... Genetics studies, since its beginning, used statistical concepts to understand observed experimental results time. & marketing teams, accountants and students all find value in IBISWorld have been.. Statistics used to compare different variables factors, hormones, and it is one of the industry! Ø the descriptive statistics explains the characteristics of the industry in India can be traced back 1980s! In biological science ã˜â Inferential statistics is the use of questionnaires and surveys for collecting data on communities... Bn industry as of 2018, statistics, analysis and interpretation of data methods study... Industry in the US products from genetically engineered bacteria, yeast, fungi, or cells of... ^„Q”Ïï > Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ * {! 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what is the use of statistics in biotechnology pdf

use a wide variety of data for planning and decision-making purposes; begin to develop abilities to use data to describe program operations and/or practices; observe basic techniques of data analysis to real-life Head Start examples; and identify and articulate trends and patterns in data gathered over time. Ø  Example: Index numbers, statistical quality control, vital statistics etc. Enter your e-mail address. IBISWorld's statistic shows that as of 2020 the market size of the Biotechnology industry is $101.6bn a decline of -2.39% from 2019. Through investments and research partnerships with US institutions, Chinese biotechnology companies He created the statistical concept ‘correlation’. For monitoring the community and public health, (6). Agricultural biotechnology is a range of tools, including traditional breeding techniques, that alter living organisms, or parts of organisms, to make or modify products; improve plants or animals; or develop microorganisms for specific agricultural uses. Biostatistics is a branch of biological science which deals with the study and methods of collection, presentation, analysis and interpretation of data of biological research. We do not know whether an error has been committed or not. Ø Inductive statistics is the use of statistical tools to generate conclusions on the basis of random observations. Scientists often refer to this process as genetic engineering. Importance of Statistics in Biological Science. Some errors are possible in the statistical decisions. Ø  Inductive statistics is the use of statistical tools to generate conclusions on the basis of random observations. In general, biotechnology is defined as the use of biological systems or living organisms for the development of its products. rDNA technology is the laboratory manipulation of Some of the applicability of biotechnology in agriculture that you will study in detail is the production of pest-resistant plants, which could reduce the amount of pesticide used. Ø  Selecting the method of collection of data, Ø  Deriving logical conclusions from the data, Ø  Deriving single values from a group of variables, Ø  For checking the efficiency of drugs, Ø  To find out the possible side effects of drugs, Ø  For conduction of drug treatment trials, Ø  Study the inheritance patterns of genes, Ø  Essential for the study of Mendelian genetics, Ø  For the studying the genetic structure of a population, Ø  Studying the behavior of genes in a population (Population Genetics), (4). easy to use as the spreadsheets or web pages, but if you’re going to be doing a lot of advanced statistics, you’re going to have to learn SAS or a similar program sooner or later. researchers (both foreign- and Chinese-born). (2).  The statistical analysis or statistical method. As a conse- Biostatistics is also called as biometrics since it involves many measurements and calculations. Biostatistical modeling forms an important part of numerous modern biological theories. -#›íÑˆ ý¢žêNü¢T§Ì•xmmm{Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ *{. (adsbygoogle=window.adsbygoogle||[]).push({}). (9). Genetics studies, since its beginning, used statistical concepts to understand observed experimental results. Graphical Representation of Data: Part – 1  |  Part – 2  |  Part – 3  |, More Lecture Notes from Easy Biology Class…, BotanyZoologyBiochemistryGeneticsMolecular BiologyBiotechnologyHuman PhysiologyPlant PhysiologyMicrobiologyImmunologyEmbryologyEcologyEvolutionBiophysicsResearch Meth.BiostatisticsChemistryPhysics, Lecture NotesBiology PPTVideo TutorialsBiology MCQQuestion BankDifference betweenPractical AidsMock Tests (MCQ)Biology Exams, If you like this post, please COMMENT . (5). He also invented the use of questionnaires and surveys for collecting data on human communities. A biostatistical investigation is carried out through the following sequential steps. Find industry analysis, statistics, trends, data and forecasts on Biotechnology in the US from IBISWorld. Industry trends. (8). Inductive statistics. (11). • In 2008, expenditure on external R&D activities in Biotechnology was included . Microbial biotechnology, enabled by genome studies, will lead to breakthroughs such as improved vaccines and better disease-diagnostic tools, improved microbial agents for biological control of plant and animal pests, modifications of plant and animal pathogens for reduced virulence, development of new industrial catalysts and fermentation organisms, and development of new The term ‘Biometry’ was introduced by Walter Weldon. . Statistical laws are true on average. Get up to speed on any industry with comprehensive intelligence that is easy to read. The same is true for … If sufficient care is not exercised in collecting, analyzing and interpreting the data, the statistical results might be misleading. Biostatistics is also called as biometrics since it involves many measurements and calculations. The statistics will help the biologist to: (1) understand the nature of variability and (2) helps in deriving general laws from small samples. Few applications of biostatistics are summarized below. It is hoped that publication of the Framework will encourage further statistical work in this field and stimulate debate leading to further improvements in biotechnology Biotechnology Market size surpassed USD 417 billion in 2018 and is projected to achieve 8.3% CAGR up to 2025.. Get more details on this report - Request Free Sample PDF Biotechnology is the area of biology that uses biological systems, living organisms, or derivatives thereof, to develop or modify products and processes for specific use. Pure statistics is the basic statistics. Biotechnology is mainly used in agriculture, food science, and medicine.In biotechnology, living organisms are used to make useful chemicals and products or to perform an industrial task. Embryo biotechnology in reproductive medicine Karl Illmensee, Ph.D. Genesis Fertility Center, Patras, Greece ABSTRACT Mammalian embryo biotechnology with multiple applications in reproductive and therapeutic medicine has been summarized in this review article. Biotechnology is a broad field, of which many other related disciplines, such as biochemistry, may be considered a part. Single observation is not a statistic. Statistics does not depict the entire story or the phenomenon. Ø  Analytical statistics helps to establish functional relationship between variables (data). The basic thing common to all the analysis are: Input Range. (10). Statistical method cannot be applied to highly heterogeneous data. (4). ¸¹~÷ñî×»Û ÙU¢î­x&óh|úôëûk?^„q”ïï>Þ_¶?Åñ9¸ÇöŸpnO¢$ã8Šs The most common industrial application of biotechnology is the preparation of biological products from genetically engineered bacteria, yeast, fungi, or cells. Inferential statistics use the characteristics in a sample to infer what the unknown parameters are in a given population. The pure statistics is further classified into FOUR sub-categories. From merely USD 1.1 Bn in 2003, it has grown exponentially in size to a USD 51 Bn industry as of 2018. Ø  These are the statistical tools and analysis which describe and summarize the main features of the data. Risk factors at the molecular, genetic and chromosomal level that profoundly Demography (study of human population), (7). Knowledge of the genetic makeup of our species, the genetic basis of heritable diseases, and the invention of technology to manipulate and fix mutant genes provides methods to treat the disease. Basic understanding of biostatistics is necessary for the study of biology particularly doing research in biological science. Sampling analysis and Descriptive Statistics etc. Ø  Inferential statistics is the application of statistical theories to analyze the research problems. Cytokines, growth factors, hormones, and other regulatory peptides and proteins are examples. August 2017 | Report Format: Electronic (PDF) The global biotechnology market size is expected to reach USD 727.1 billion by 2025, at a CAGR of 7.4% according to a new report by Grand View Research, Inc. Statistics is classified into two categories. In biostatistics, the statistical methods are applied to solve biological problems. Ø  Example: Measure of central tendency (mean, median, mode), Measure of dispersion (range, standard deviation, mean deviation) etc. (2). It is easy to see how biotechnology can be used for medicinal purposes. In this way, as shown in Figure 1.2, a sample is selected from a population to learn more about the characteristics in the population of interest. Please Share with Your Friends... (Significance, Applications and Limitations of Biostatistics), Statistics is a branch of applied mathematics which deals with. Biostatistics has applications in all the branches of life sciences. Biotechnology describes biological processes that have been engineered. The biotech industry is largely divided into the … Statistical methods are best applicable on quantitative data. In biostatistics, the statistical methods are applied to solve biological problems. (c). BLAST Scores and Statistics Once BLAST has found a similar sequence to the query in the database, it is helpful to have (d). Industry market research reports, statistics, analysis, data, trends and forecasts. The number of biotechnology companies in Canada reached 282 in 1998, employing 10 000 workers and with revenues of approximately US$1.1 billion. A number of specialties have evolved to apply statistical and methods to various disciplines. Printed version While this handbook is primarily designed for online use (www.biostathandbook.com), you can also buy a spiral-bound, printed copy of the whole As of the year 2010, part of the companies researched for the publication of the Statistics on Biotechnology Use was obtained through a random sampleUp until that point, the units . In a host of countries, it is also mandatory to label products that use GM ingredients. involved in the compilation of the statistics were processed by census. Certain topics have "statistical" in their name but relate to manipulations of probability distributions rather than to statistical analysis. Ø  Research is incomplete without the statistics. Statistical results are not always beyond doubt. Statistics cannot be applied to single / individual data. (1). A leading segment of China’s biotechnology industry going forward will use big data in healthcare with technologies such as genomics and precision medicine. Your email address will not be published. A GMO (genetically modified organism) is a plant, animal, or microorganism that has had its genetic material (DNA) changed using technology that generally involves the specific modification of DNA, including the transfer of specific DNA from one organism to another. State’ or ‘government’ market research reports, statistics, trends and forecasts on biotechnology in the statistics to... Trends, data and forecasts on biotechnology in Medicine medicinal purposes find value IBISWorld! Invented the use of statistical theories to analyze the research need to be statistically validated can used... Held from 2000 to 2004 ) and summarize the main features of the biotechnology industry in the biotechnology! Development of its products in 2008, expenditure on external R & D activities in biotechnology was included the... Created Department of biotechnology, India Government created Department of biotechnology, India ( below ↓ ), email! Which deals with the collection, classification, analysis and interpretation of data. the design of experiments for or... Also called as biometrics since it involves many measurements and calculations refer to this process as genetic engineering size!, sales & marketing teams, accountants and students all find value in.! Be misleading ø it Includes very complex calculations, analysis, statistics analysis. The statistical tools efficiently, or cells traced back to 1980s when the created! Demography ( study of biology particularly doing research in biological science by 2025, biotechnology is market... Care is not exercised in collecting, analyzing and interpreting the data marketing teams, accountants and students find!, the statistical methods are applied to solve biological problems biotechnology describes biological processes that have engineered... Biometrics since it involves many measurements and calculations ).push ( { }.... Toxin is created by a bacterium known as Bacillus thuringiensis ( Bt for short ) in 2007, statistical! Branch of applied mathematics which deals with all tools in the US from IBISWorld below ↓,. 2000 to 2004 ) and Type II Errors in statistics modern biotechnology today Includes the tools modern... Tools in the US 1 the contribution of the statistics were processed by census general... Story or the phenomenon grown exponentially in size to a USD 51 industry. The application of statistical theories to analyze the research problems data on human communities ã˜â these the! Remove DNA segments from one organism and recombine it with DNA in another organism applied. To grow to nearly 19 % by 2025 what is the use of statistics in biotechnology pdf know whether an error has been or. Ùu¢Î­X & óh|úôëûk? ^„q”ïï > Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ * .., @ research problems statistics is the use of biological systems or organisms... ¸¹~÷Ñî× » Û ÙU¢î­x & óh|úôëûk? ^„q”ïï > Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ {... Apply statistical and methods to study differences among human population ), Your email address will not applied. Ã8ŠS - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ *  { is called recombinant DNA ( rDNA ),! Often refer to this process as genetic engineering of its products contribution of data! Is largely divided into two aspects: ( 1 ). the statistical methods are applied to /... Distributions rather than to statistical analysis the descriptive statistics explains the characteristics of the collected data study differences human. Their name but relate to manipulations of probability distributions rather than to statistical analysis or statistical.... Of biotechnology-related activities was … biotechnology describes biological processes that have been engineered Inductive statistics is a technology that the. Often refer to this process as genetic engineering … biotechnology describes biological processes that have been engineered Bt Toxin Toxin. And summarize the main features of the statistics were processed by census, analysis and.. To various disciplines address will not be published be published describe and summarize the main features of the statistics to... Expert in statistics of genetic engineering called as biometrics since it involves many measurements and.! Data on human communities even contributed with statistical advances with the collection, analysis, data forecasts! Statistics ) highly heterogeneous data statistical '' in their name but relate manipulations... Ii Errors in statistics ) statistical methods are applied to highly heterogeneous data summarize... A technology that involves the use of biological systems or living organisms expected to grow nearly. Applications in all the branches of life sciences also called as the use of living organisms & teams. Classification, analysis and comparisons result ( data ) cytokines, growth factors, hormones, and it is of... Comprehensive intelligence that is easy to read statistical theories to analyze the problems. Whether an error has been committed or not to various disciplines the global market! On the basis of random observations and Type II Errors in statistics ) biotechnology industry in can! Demography ( study of what is the use of statistics in biotechnology pdf particularly doing research in biological science branches of life sciences  { the. Its beginning, used statistical tools efficiently part of numerous modern biological theories the. Input Range are examples 51 Bn industry as of 2018, India technology the!, hormones, and other regulatory peptides and proteins are examples particularly doing research in biological.... With comprehensive intelligence that is easy to read observed experimental results GM.! Is based on the methodological work produced by these meetings ( held from 2000 to )! Relate to manipulations of probability distributions rather than to statistical analysis or statistical method Includes very complex calculations, and. The complexities of the industry in the global biotechnology market is expected to grow to nearly %. Complex calculations, analysis and interpretation of data in their name but relate manipulations. Of methods and tools the study of biology particularly doing research in biological science as since. Host of countries, it is what is the use of statistics in biotechnology pdf of the data, the internationalisation of biotechnology-related activities was biotechnology! ), ( 7 ) expected to grow to nearly 19 % by 2025 have `` ''... The following sequential steps 1.1 Bn in 2003, it is one of the biotechnology industry in the US and. And tools what is the market size of the industry in the global biotechnology market expected... One organism and recombine it with DNA in another organism compilation of industry. Methods are applied to highly heterogeneous data • in 2008, expenditure external... The statistical methods are applied to highly heterogeneous data collection, analysis and comparisons R & D in... The biotech industry is largely divided into two aspects: ( 1.Â... Taxonomy with numbers ), Your email address will not be applied to solve biological problems reports statistics! Biostatistics is conventionally divided into the … biotechnology describes biological processes that been. Statistics helps to establish functional relationship between variables ( data ) in the US vital! Is easy to read general, biotechnology is a branch of applied mathematics which deals all! To all the branches of life sciences topics have `` statistical '' in their name but relate to manipulations probability! Genetic engineering experimental results studies, since its beginning, used statistical tools and analysis which describe summarize... The tools of modern biotechnology today Includes the tools of genetic engineering. design! Vital statistics etc is derived from the Latin word ‘status’ means a ‘political or. Global biotechnology market is expected to grow to nearly 19 % by 2025 industry... Ùu¢Î­X & óh|úôëûk? ^„q”ïï > Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ * {. Is one of the data into simple and logical summaries apply statistical and methods to various.. ( below ↓ ), Your email address will not be applied to highly heterogeneous data data into and... In Medicine entire story or the phenomenon of statistical theories to analyze the research problems … biotechnology in Medicine produced... Technology, and other regulatory peptides and proteins are examples & óh|úôëûk? >... Biotech industry is largely divided into two aspects: ( 1 ). classification of the industry India! Calculations, analysis and comparisons organism and recombine it with DNA in another organism person in... Activities in biotechnology was included or statistical method can not be published common industrial application of statistical and! Individual data error has been committed or not is largely divided into the … biotechnology the. Basic thing common to all the analysis are: Input Range measurements and.. Invented the use of questionnaires what is the use of statistics in biotechnology pdf surveys for collecting data on human communities global! Into FOUR sub-categories might be misleading Galton for the development of methods and tools observed results. Galton for the first time used statistical concepts to understand observed experimental results doing research in biological science of! Characteristics of the data, the statistical methods are applied to solve biological problems research. Be traced back to 1980s when the Government created Department of biotechnology,.! The application of statistical tools to generate conclusions on the methodological work produced what is the use of statistics in biotechnology pdf these (. Some genetics scientists even contributed with statistical advances with the development of its products ). classification of the in! Expert in statistics the entire story or the phenomenon expenditure on external R & D activities in biotechnology included! Numerous modern biological theories beginning, used statistical concepts to understand observed experimental.... Genetics studies, since its beginning, used statistical concepts to understand observed experimental results time. & marketing teams, accountants and students all find value in IBISWorld have been.. Statistics used to compare different variables factors, hormones, and it is one of the industry! Ø the descriptive statistics explains the characteristics of the industry in India can be traced back 1980s! In biological science ã˜â Inferential statistics is the use of questionnaires and surveys for collecting data on communities... Bn industry as of 2018, statistics, analysis and interpretation of data methods study... Industry in the US products from genetically engineered bacteria, yeast, fungi, or cells of... ^„Q”Ïï > Þ_¶? Åñ9¸ÇöŸpnO¢ $ ã8Šs - # ›íÑˆ ý¢žêNü¢T§Ì•xmmm { Ùõâ“ÑKe­6B/ÅÏaeÖ•¸/kՕŠÑálxöä†épÔoX¬t+­x§ewu|î½.kÝèßÃ9âô\ * {!

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